A Comparison of Propranolol with Steroid in the Treatment of Hemangioma in Children In Terms Of Regression in Size

Adnan Ghafoor; Bashir Ur Rahman; Asma Bibi; Muhammad Taimur

Abstract:

OBJECTIVE: To compare the efficacy of Propranolol with steroid (oral prednisolone) in treating the children with cutaneous haemangioma in terms of frequency of size reduction. STUDY DESIGN: A Randomized Comparative Trial PLACE AND DURATION: Department of Pediatric Surgery at Children Hospital PIMS Islamabad from 9th July 2013 to 9th Jan 2014. METHODOLOGY: Total 60 children having cutaneous haemangiomas at any site were studied. Patients were randomly divided and in Group A 30 patients were given oral propranolol while 30 patients in Group B were given oral prednisolone for treating haemangiomas. Patients had an age range one month to 12 years. Patients were followed for one month to see >75% Regression in size of haemangioma in each dimension for each group. RESULTS: The >75% regression in size in Group A was 93.3% (n=28) and in Group B was 0% (n=0) with p value 0.000. CONCLUSION: Oral propranolol is more effective treatment of haemangioma than oral steroid used for same duration in terms of size reduction with no major side effects of treatment. KEY WORDS: Infantile, Cutaneous haemangioma, Size regression, Propranolol, Steroid, Efficacy

research from:

• Foundation University Medical College

Year:

2018

Type of Publication:

Article

Journal:

Isra Medical Journal

Volume:

10

Number:

1

Pages:

-

Month:

1-2