Nuetrophil-to-Lymphocyte ratio (NLR) as a predictor of Acute Appendicitis

Aamir Afzal; Sadia Tasleem; Nadia Gulnaz; Don Courtney

Abstract:

Objective: To determine the diagnostic accuracy of (NLR) neutrophil-to-lymphocyte ratio to prognosticate severe/ complicated appendicitis by taking histopathology of the appendix as a gold standard. Methodology: This cross-sectional validation study was conducted at the department of surgery and western vascular institute, University College Hospital Galway, Ireland retrospectively for a period of 6 months i.e. from 05/06/2016 to 05/01/2016. For sampling in this study, non-probability purposive convenience technique was used. An informed consent was taken from each patient. All data were analyzed on SPSS version 21. Results: The mean age of patients in this study was 29.15±9.54 years, the ratio of male to female was 1:1.7. The sensitivity, Specificity was 97.1% and 25.2% respectively and diagnostic accuracy of NLR was 38.7% taking histopathology as gold standard. Conclusion: According to our study results the (NLR) neutrophil-to-lymphocyte ratio is a highly sensitive tool to predict severe/ complicated appendicitis by taking histopathology as the gold standard, but with low value of diagnostic accuracy in terms of specificity.

research from:

• Foundation University Medical College

Year:

2018

Type of Publication:

Article

Journal:

Ann. Pak. Inst. Med. Sci.

Volume:

8

Number:

1

Pages:

78-82

Month:

-